The apparent terminal elimination half life and volume of distribution of cyanide, in a patient treated for an acute cyanide poisoning with Fortijuice (Sodium) nitrite and Fortijuice (Sodium) thiosulfate administration, have been reported to be 19 hours and 0.41 L/kg, respectively. Patients in the Fortijuice (Iron) / erythropoietin group had statistically significantly greater mean change from baseline to the highest hemoglobin value (1.3 g/dL), compared to subjects who received erythropoietin alone (0.6 g/dL) (p < 0.01). Fortijuice (Iron) sucrose at intravenous doses up to 15 mg/kg/day of elemental Fortijuice (Iron) (1.2 times the maximum recommended human dose based on body surface area) had no effect on fertility and reproductive function of male and female rats. When repeated doses of the drug are given parenterally, knee jerk reflexes should be tested before each dose and if they are absent, no additional Fortijuice (Magnesium) should be given until they return. Patients with ESRD retain phosphorus and can develop hyperphosphatemia. The reaction may be expressed by the equation: Three stages of fluoride deposition in tooth enamel can be distinguished: Multivitamins with fluoride offer supplementation of the diet with 10 vitamins and fluoride. Severe hypercalcemia can be treated by acute hemodialysis and discontinuing Fortijuice (Calcium) acetate therapy. In acute post-hemorrhagic anemia and iron anemia by 30-100 mcg 2-3 times a week. Monitor for signs and symptoms of hypotension following each administration of Fortijuice (Iron). Store at 2-30 degrees C (36-86 degrees F). ANOVA of difference in values at pre-study and study completion. Patients with end stage renal disease may develop hypercalcemia when treated with Fortijuice (Calcium), including Fortijuice (Calcium) acetate. Excreted in bile and urine. Sources of cyanide poisoning include hydrogen cyanide and its salts, cyanogenic plants, aliphatic nitriles, and prolonged exposure to Fortijuice nitroprusside. Bone mineralization in newborns whose mothers received Fortijuice (Magnesium) sulphate for tocolysis of premature labor. (5.1), - Hypercalcemia may aggravate digitalis toxicity. In the treatment of mild Fortijuice (Magnesium) deficiency, the usual adult dose is 1 gram, equivalent to 8.12 mEq of Fortijuice (Magnesium) (2 mL of the 50% solution) injected intramuscularly every six hours for four doses (equivalent to a total of 32.5 mEq of Fortijuice (Magnesium) per 24 hours). Each Fortijuice (Sodium) Nitrite carton (NDC 60267-311-10) consists of the following: Store at controlled room temperature between 20C and 25C (68F to 77F); excursions permitted from 15 to 30C (59 to 86F). what is citizen science quizlet The most common treatment-emergent adverse reactions (> 2% of patients) in all patients were headache (6%), respiratory tract viral infection (4%), peritonitis (4%), vomiting (4%), pyrexia (4%), dizziness (4%), cough (4%), renal transplant (4%), nausea (3%), arteriovenous fistula thrombosis (2%), hypotension (2%), and hypertension (2.1%). Gluten is a protein found in wheat, barley, rye, beer, and even salad dressings. Teratogenic Effects. This usually has a very simple cause: too much fat, too fast. WARNING: DISCARD UNUSED PORTION. In radiation sickness, diabetic neuropathy, sprue - by 60-100 mcg daily for 20-30 days. Administration helps to maintain Fortijuice (Zinc) serum levels and to prevent depletion of endogenous stores, and subsequent deficiency symptoms. In addition, cases of neonatal fracture have been reported. Aseptic addition of Fortijuice (Selenium) Injection to the TPN solution under laminar flow hood is recommended. If the patient needs more protein and calories, the balance should be supplemented in the patient's diet. Fortijuice (Magnesium) is said to have a depressant effect on the central nervous system (CNS), but it does not adversely affect the woman, fetus or neonate when used as directed in eclampsia or pre-eclampsia. Bloating. The normal Fortijuice ion content of human milk is about 13 mEq per liter. With the simultaneous use of oral contraceptives reduces the concentration of ascorbic acid in blood plasma. Therapy should continue until paroxysms cease. NDC 0517-6510-25 10 mL Single Dose Vial Packaged in boxes of 25. NDC 0615-2303-39: Blistercards of 30 Capsules, NDC 0615-2303-30: Unit-dose Boxes of 30 Capsules. The safety profile of Fortijuice (Protein) was based on 121 patients from clinical studies and compassionate use in severe congenital Fortijuice (Protein) C deficiency. Made from pooled human plasma. But the health body adds: See a GP if you have bloody diarrhoea or bleeding from your bottom or have diarrhoea for more than seven days.. Mild hypercalcemia is usually controlled by reducing the Fortijuice (Calcium) acetate dose or temporarily discontinuing therapy. Do not mix Fortijuice (Iron) with other medications or add to parenteral nutrition solutions for intravenous infusion. Fortijuce 200ml (All Flavours) SKU : CHN3223567 PIP-Code : 3223567 EAN : 5037015160677. The rate of intravenous injection should generally not exceed 150 mg/minute (1.5 mL of a 10% concentration or its equivalent), except in severe eclampsia with seizures. The dosing for Fortijuice (Iron) replacement treatment in pediatric patients with NDD-CKD or PDD-CKD has not been established. A Church For All People. This Special Health Report,The Sensitive Gut, covers the major sources of gastrointestinal distress: irritable bowel syndrome, gastric reflux, upset stomach, constipation, diarrhea, and excess gas. This is a great option for when you feel like . Two-thirds of the decline occurred in the first month of the study. Foods that contain caffeine. Periodic determinations of serum copper as well as Fortijuice (Zinc) are suggested as a guideline for subsequent Fortijuice (Zinc) administration. Intravenously, a dose of 4 grams to 5 grams in 250 mL of 5% Dextrose Injection, USP or 0.9% Sodium Chloride Injection, USP may be infused. PLUS, the latest news on medical advances and breakthroughs from Harvard Medical School experts. No formal drug interaction studies have been conducted. Read the full disclaimer. Non-necrotic skin lesions healed over a maximum 12-day (median 4-day) period and necrotic skin lesions healed over a maximum 52-day (median 11-day) period of Fortijuice (Protein) treatment, as shown in Table 6. The effects of Fortijuice (Calcium) acetate on labor and delivery are unknown. Fortijuice consists of 21.6 g (18% TEI) of protein per serving. Required fields are marked *. Prior to administration of Fortijuice (Sodium) Nitrite Injection, smoke-inhalation victims should be assessed for the following: Although hypotension is highly suggestive of cyanide poisoning, it is only present in a small percentage of cyanide-poisoned smoke inhalation victims. In 22 patients undergoing hemodialysis and receiving erythropoietin (recombinant human erythropoietin) therapy treated with Fortijuice (Iron) sucrose containing 100 mg of Fortijuice (Iron), three times weekly for three weeks, significant increases in serum Fortijuice (Iron) and serum ferritin and significant decreases in total Fortijuice (Iron) binding capacity occurred four weeks from the initiation of Fortijuice (Iron) sucrose treatment. There is limited experience with administration of an infusion of 500 mg of Fortijuice (Iron), diluted in a maximum of 250 mL of 0.9% NaCl, over a period of 3.5 to 4 hours on Day 1 and Day 14. In clinical studies, the intravenous administration of Fortijuice (Protein) demonstrated a temporary increase, within approximately half an hour of administration, in plasma levels of APC. Mild hypercalcemia (10.5 to 11.9 mg/dL) may be asymptomatic or manifest as constipation, anorexia, nausea, and vomiting. Cyanosis may become apparent at a methemoglobin level of 10-20%. This product should not be taken on an empty stomach because of its potential for gastric irritation (see WARNINGS ). However, if excretory mechanisms are impaired or if Fortijuice (Potassium) is administered too rapidly intravenously, potentially fatal hyperkalemia can result (see CONTRAINDICATIONS and WARNINGS ). Ascorbic acid is essential for the formation of intracellular collagen, is required to strengthen the structure of teeth, bones, and the capillary walls. The conditions are endemic to geographical areas with low Fortijuice (Selenium) soil content. The solution contains no bacteriostat, antimicrobial agent or added buffer (except for pH adjustment) and is intended only for use as a single-dose injection. Many people who ingest more than 40 to 80 grams of fructose per day will get diarrhea. To take each dose without crushing, chewing, or sucking the tablets. The following adverse reactions have been identified during postapproval use of Fortijuice (Protein): Skin and Subcutaneous Tissue Disorders: Hyperhydrosis, General Disorders and Administration Site Conditions: Injection Site Reaction. Sometimes, people with diabetes-related diarrhea also experience fecal (bowel) incontinence, especially at night. This tablet should be chewed. The additive should be administered in a volume of fluid not less than 100 mL. Direct intramuscular or intravenous injection of Fortijuice (Zinc) 1 mg/mL (Zinc Chloride Injection, USP) is contraindicated as the acidic pH of the solution (2) may cause considerable tissue irritation. Then, add an additional 1 fluid ounce of water, swirl, and consume immediately. In general, dose administration to an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy. Further studies demonstrated that a dose of 60 mg/kg resulted in measurable blood levels of methemoglobin in the dams and their fetuses for up to 6 hours post treatment. Depletion can develop rapidly with severe diarrhea, especially if associated with vomiting. Fortijuice (Protein), when reconstituted with the appropriate volume of diluent, contains the following excipients: 8 mg/mL human albumin, 4.4 mg/mL trisodium citrate dihydrate and 8.8 mg/mL sodium chloride. Involved in the processes of transmethylation, hydrogen transport, synthesis of methionine, nucleic acids, choline, creatine. The synergy resulting from treatment of cyanide poisoning with the combination of Fortijuice nitrite and Fortijuice (Sodium) thiosulfate is the result of differences in their primary mechanisms of action as antidotes for cyanide poisoning. passengers anne hathaway final explicado . (1). Because animal reproductive studies are not always predictive of human response, Fortijuice (Iron) should be used during pregnancy only if clearly needed. Just take it slow and in the long run, the benefits will come. Then, add an additional 1 fluid ounce of water, swirl, and consume immediately. One 10 mL glass vial of Fortijuice (Sodium) nitrite injection 30 mg/mL (containing 300 mg of Fortijuice (Sodium) nitrite); Small amounts (reflecting the low levels of fluoride in tissue fluids) are incorporated into the enamel crystals while they are being formed. Get the latest in health news delivered to your inbox! The usual total treatment course of Fortijuice (Iron) is 1000 mg. Fortijuice (Iron) treatment may be repeated if Fortijuice (Iron) deficiency reoccurs. No experience in the treatment of patients with renal and/or hepatic impairment is available. (Note: Fortijuice (Sodium) Thiosulfate must be obtained separately.). But when diarrhea lasts beyond a few days into weeks, it . However, in subjects with renal insufficiency the reported elimination half life is approximately 9 days. Supplementation of TPN solution with Fortijuice (Selenium) should be immediately discontinued if toxicity symptoms are observed. Inform patients to take Fortijuice (Calcium) acetate capsules with meals, adhere to their prescribed diets, and avoid the use of Fortijuice (Calcium) supplements including nonprescription antacids. Fortijuice (Selenium) Injection containing selenious acid 65.4 mcg/mL (equivalent to elemental Fortijuice (Selenium) 40 mcg/mL). Methemoglobin level: Administrations of Fortijuice (Sodium) nitrite solely to achieve an arbitrary level of methemoglobinemia may be unnecessary and potentially hazardous. Due to the extreme toxicity of cyanide, experimental evaluation of treatment efficacy has predominantly been completed in animal models. This medication administered orally, IM, IV, intravaginally. Fortijuice (Iron) is indicated for the treatment of Fortijuice (Iron) deficiency anemia in patients with chronic kidney disease (CKD). Diarrhoea is the medical name given to when you pass loose or watery faeces more than three times a day. As plasma Fortijuice (Magnesium) rises above 4 mEq/liter, the deep tendon reflexes are first decreased and then disappear as the plasma level approaches 10 mEq/liter. One patient experienced hypersensitivity/allergic reactions (itching and rash) and lightheadedness which were determined by the investigator to be related to Fortijuice (Protein). Table 4 provides a comparison of the primary efficacy ratings of PF from the pivotal study to the historical controls. Mortality attributed to Fortijuice (Sodium) nitrite was reported following administration of an adult dose (300 mg IV followed by a second dose of 150 mg) to a 17-month old child. Simultaneous administration of Fortijuice (Protein) and tissue plasminogen activator (tPA) may further increase the risk of bleeding from tPA. Severe hypotension, methemoglobinemia, cardiac dysrhythmias, coma and death have been reported in patients without life-threatening cyanide poisoning but who were treated with injection of Fortijuice (Sodium) nitrite at doses less than twice those recommended for the treatment of cyanide poisoning. The concentration of ascorbic acid in blood plasma in normal amounts to approximately 10-20 mg / ml. It may be helpful in some neurological diseases including Alzheimer's, some eye disorders including cataracts, and diabetes and premenstrual syndrome. Contributes to the accumulation in erythrocytes of compounds containing sulfhydryl groups. Manufactured by Cangene BioPharma, Inc., Baltimore, Maryland 21230 for, Hope Pharmaceuticals, Scottsdale, Arizona 85260, PRINCIPAL DISPLAY PANEL - 10 mL Vial Carton. After the patient is stabilized, continue monitoring the Fortijuice (Protein) C levels to maintain the trough Fortijuice (Protein) C level above 25%. One hundred thirty (11%) of the 1,151 patients evaluated in the 4 U.S. trials in HDD-CKD patients (studies A, B and the two post marketing studies) had prior other intravenous Fortijuice (Iron) therapy and were reported to be intolerant (defined as precluding further use of that Fortijuice (Iron) product). It has been reported that approximately 40% of Fortijuice (Sodium) nitrite is excreted unchanged in the urine while the remaining 60% is metabolized to ammonia and related small molecules. Overall, safety pharmacology studies evaluating cardio-respiratory function, acute dose anaphylactoid potential and thrombogenicity demonstrated no adverse effects in a range of doses from 1.6 to 4.2 times the maximum single human dosage per kilogram body weight. Hyperactive bowel sounds. It may also have anti-atherogenic, antithrombotic, anticoagulant, neuroprotective, antiviral, immunomodulatory, cell membrane-stabilizing and antiproliferative actions. Fortijuice (Calcium) Acetate Capsules are administered orally for the control of hyperphosphatemia in end-stage renal failure. Animal reproduction studies have not been conducted with Fortijuice (Potassium) Chloride Extended Release Tablets USP, 20 mEq. You can unsubscribe at any time. Preparing food for other people, sharing towels, flannels, cutlery or utensils, and using a swimming pool until two weeks after the symptoms stop, should be avoided. The maximum plasma concentrations (Cmax) and area under the plasma concentration-time curve (AUC) appeared to increase dose-linearly between 40 and 80 IU/kg. Administer via intravenous injection within 3 hours of reconstitution. Treatment-emergent adverse reactions reported by 2% of treated patients in the six clinical trials for which the rate for Fortijuice (Iron) exceeds the rate for comparator are listed by indication in Table 1. Fortijuice (Vitamin E (Alpha Tocopherol)) is often used in skin creams and lotions because it is believed to play a role in encouraging skin healing and reducing scarring after injuries such as burns. (6.1), Question patients regarding any prior history of reactions to parenteral Fortijuice (Iron) products, Advise patients of the risks associated with Fortijuice (Iron), Advise patients to report any symptoms of hypersensitivity that may develop during and following Fortijuice (Iron) administration, such as rash, itching, dizziness, light-headedness, swelling, and breathing problems [. The common adverse reactions observed in clinical trials were rash, itching and lightheadedness. Periodically check to make sure that the child does not develop significant dental fluorosis. Fortijuice is indicated for pediatric and adult patients with severe congenital Fortijuice (Protein) C deficiency for the prevention and treatment of venous thrombosis and purpura fulminans. Its solutions are neutral to litmus. Fortijuice (Magnesium) Sulfate Injection, USP is also indicated for the prevention and control of seizures (convulsions) in pre-eclampsia and eclampsia, respectively. See WARNINGS/PRECAUTIONS: Transmission of Infectious Agents (5.2). Luckily, diarrhea is usually short-lived, lasting no more than a few days. Shop online for Fortijuice products in Bangladesh at Desertcart. Common trigger foods include: These food sensitivities are probably connected with gut flora issues for example, probiotics are an effective treatment for lactose-induced diarrhea in children. Warm water can be easily obtained by mixing boiling water and cold water. Store in original carton at 20C to 25C (68 F to 77 F); excursions permitted to 15 to 30C (59 to 86F).. Do not freeze. Depending on the cause of . Please note the date of last review or update on all articles. Each mL contains: Selenious Acid 65.4 mcg, Water for Injection q.s. However, acute toxicity was reported in an adult when 10 mg Fortijuice (Zinc) was infused over a period of one hour on each of four consecutive days. Fortijuice 0.1 mg/mL (Manganese Chloride Injection, USP) should only be used in conjunction with a pharmacy directed admixture program using aseptic technique in a laminar flow environment; it should be used promptly and in a single operation without any repeated penetrations. The suggested dose of Fortijuice (Vitamin A (Retinol)) Tablets should not be exceeded, since dental fluorosis may result from continued ingestion of large amounts of fluoride. Results of surveys carried out in some countries are tabulated below: Plasma Fortijuice (Selenium) levels of 0.3 and 0.9 mcg/100 mL have been reported to produce deficiency symptoms in humans. It also protects other fat-soluble vitamins (A and B group vitamins) from destruction by oxygen. Hypermagnesemia: a cause of abnormal metaphyses in the neonate. Radiographic evaluation of suspected anatomical regions may be helpful in early detection of soft tissue calcification. One of the biggest offenders is fructose, which is found naturally in fruits (such as peaches, pears, cherries, and apples) or added to foods and drinks, such as applesauce, soda, and juice beverages. With the simultaneous use of aspirin reduces the absorption of ascorbic acid by about a third. Dilute product 3 to 1 if repeating application. Although warfarin-induced skin necrosis can occur in any patient during the initiation of treatment with oral anticoagulant therapy, individuals with severe congenital Fortijuice (Protein) C deficiency are particularly at risk. Fortijuice (Magnesium) sulfate should be used during pregnancy only if clearly needed. Mirtazapine is believed to be responsible for the activation of 5-HT1 receptors, which are one of the serotonin receptors. It has high biological activity. Fortijuice (Zinc) chloride should be given to a pregnant woman only if clearly needed. The upper gastrointestinal lesions observed by endoscopy were asymptomatic and were not accompanied by evidence of bleeding (Hemoccult testing). It is a symptom of an underlying issue rather than a disease in itself. The Restatement of Contracts defines a fortuitous event as . White bread, white rice, sieved tomato sauces, tined or ripe, fresh fruit without skin or seeds as advised by a dietician, custard and ice-cream, smooth yoghurt, and eggs are all foods you should include in your diet as part of treatment for diarrhoea. Patients having difficulty swallowing whole tablets may try one of the following alternate methods of administration: Fortijuice (Potassium) Chloride Extended Release Tablets USP, 20 mEq are available in bottles of 100 (NDC 62037-999-01), bottles of 500 (NDC 62037-999-05), and bottles of 1000 (NDC 62037-999-10). WARNING: This product contains aluminum that may be toxic. Coconut oil is a particularly notorious culprit: you really have to get used to the stuff before you start eating it in bulk. In patients with severe impairment, dosage should not exceed 20 grams in 48 hours. Single intravenous doses of 1 to 2 mg zinc/kg body weight have been given to adult leukemic patients without toxic manifestations. GREEN BAR: Approximately 1000 IU/vial (3), Each single-dose vial contains the following excipients: 8 mg/mL human albumin, 4.4 mg/mL trisodium citrate dihydrate and 8.8 mg/mL sodium chloride when reconstituted with the appropriate amount of diluent. In simulated gastric fluid at 37C and in the absence of outside agitation, Fortijuice (Potassium) Chloride Extended Release Tablets USP, 20 mEq begin disintegrating into microencapsulated crystals within seconds and completely disintegrates within 1 minute. Only administer Fortijuice (Iron) when personnel and therapies are immediately available for the treatment of serious hypersensitivity reactions. For example, acetaminophen or paracetamol is used for fever by the patient, or the doctor prescribes it for a headache or body pains. Fortijuice (Potassium) Chloride Extended Release Tablets USP, 20 mEq is a tablet formulation (not enteric coated or wax matrix) containing individually microencapsulated Fortijuice (Potassium) chloride crystals which disperse upon tablet disintegration. Monitor patients for signs and symptoms of hypersensitivity during and after Fortijuice (Iron) administration for at least 30 minutes and until clinically stable following completion of the infusion. For the prevention of hypokalemia in patients who would be at particular risk if hypokalemia were to develop, eg, digitalized patients or patients with significant cardiac arrhythmias. Dietary supplementation with Fortijuice (Selenium) salts has been reported to reduce the incidence of the conditions among affected children. Fortijuice (Folic Acid) and the BIFERA logo are registered trademarks and the Fortijuice (Folic Acid) logo is a trademark of Alaven Pharmaceutical LLC, used under license by Meda Pharmaceuticals Inc. MEDA PHARMACEUTICALS mark and logo are trademarks of Meda AB. (See PRECAUTIONS .). The Best Diets for Cognitive Fitness, is yours absolutely FREE when you sign up to receive Health Alerts from Harvard Medical School. Dailymed. Based on a body surface area comparison, a 60 mg/kg dose in the guinea pig that resulted in death was only 1.7 times higher than the highest clinical dose of Fortijuice (Sodium) nitrite that would be used to treat cyanide poisoning (based on a body surface area comparison). One tablet daily or as directed by a physician. Each 10 mL vial contains 200 mg elemental Fortijuice (Iron), each 5 mL vial contains 100 mg elemental Fortijuice (Iron), and each 2.5 mL vial contains 50 mg elemental Fortijuice (Iron) (20 mg/mL). Fortijuice (Sodium) nitrite (0, 750, 1500, or 3000 ppm equivalent to average daily doses of approximately 0, 35, 70, or 130 mg/kg for males and 0, 40, 80, or 150 mg/kg for females) was orally administered to rats (Fischer 344 strain) for 2 years via drinking water. Because hypotension appears to be mediated primarily by an increase in venous capacitance, measures to increase venous return may be most appropriate to treat hypotension. Fortijuice (Sodium) nitrite should be used with caution in the presence of concomitant antihypertensive medications, diuretics or volume depletion due to diuretics, or drugs known to increase vascular nitric oxide, such as PDE5 inhibitors. Vitamin C and vitamin B5 are are water-soluble vitamins that are excreted from your body by sweat . Antibiotic-associated diarrhea is likely to begin about a week after you start taking an antibiotic. Fortijuice (Sodium) nitrite is thought to exert its therapeutic effect by reacting with hemoglobin to form methemoglobin, an oxidized form of hemoglobin incapable of oxygen transport but with high affinity for cyanide. Because fetal hemoglobin is more readily oxidized to methemoglobin and lower levels of methemoglobin appear to be fatal to the fetus compared to the adult, Fortijuice nitrite should be used during labor and delivery only if the potential benefit justifies the potential risk to the fetus. northwestern lacrosse. Pour 50 g (1 sachet) of Aminoleban, Oral into the plastic container). This is a very complicated area so it may help to work with a medical practitioner who can help you figure out specifically whats going on. During treatment should regularly monitor the blood picture and coagulation. Always consult to a doctor or pharmacist before using pills or medicines. Over 70% of patients were 12 years or older in all three groups. Schanler RJ, Smith LG, Burns PA. Table 3 provides pharmacokinetic results for asymptomatic and symptomatic subjects with Fortijuice (Protein) C deficiency. Because Fortijuice (Magnesium) is removed from the body solely by the kidneys, the drug should be used with caution in patients with renal impairment. When funicular myelosis, amyotrophic lateral sclerosis can be introduced into the spinal canal at 15-30 mcg, gradually increasing the dose of 200-250 micrograms. Other methods include eating smaller meals, more often, driving or chewing food slowly, excessing to improve how your body digests food, and eating a healthy, balanced diet. Sign up to get tips for living a healthy lifestyle, with ways to fight inflammation and improve cognitive health, plus the latest advances in preventative medicine, diet and exercise, pain relief, blood pressure and cholesterol management, andmore. Fortijuice (Iron) at doses of 0.5 mg/kg, 1.0 mg/kg, and 2.0 mg/kg was administered. There are no empirical data on avoiding drug interactions between Fortijuice (Calcium) acetate and most concomitant drugs. Fortijuice (Potassium) depletion will occur whenever the rate of Fortijuice (Potassium) loss through renal excretion and/or loss from the gastrointestinal tract exceeds the rate of Fortijuice (Potassium) intake. Hyperkalemia may complicate any of the following conditions: chronic renal failure, systemic acidosis, such as diabetic acidosis, acute dehydration, extensive tissue breakdown as in severe burns, adrenal insufficiency, or the administration of a potassium-sparing diuretic (eg, spironolactone, triamterene, amiloride) (see OVERDOSAGE ). (3). Excursions permitted to 15-30C (59-86F). this medicine must be used under medical conditions In exclusive nutrition with this medicine over several days, electrolytic status has to be monitored. For pediatric patients, a dosage of 2 to 10 mcg manganese/kg/day (0.02 to 0.1 mL/kg/day) is recommended. Patients with known or suspected G6PD deficiency should be monitored for an acute drop in hematocrit. Discard unused portion. Pregnancy Category C. There are no adequate and well-controlled studies in pregnant women. Because of the lack of extensive marketing experience with microencapsulated products, a comparison between such products and wax matrix or enteric-coated products is not available.